Photoactivated miR-148b–nanoparticle conjugates improve closure of critical size mouse calvarial defects
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چکیده
منابع مشابه
Adipose-Derived Purified PSCs Heal Critical-Size Mouse Calvarial Defects
Askarinam, A; Zara, JN; James, AW; Yuan, W; Chiang, M; Nguyen, A; Stoker, D; Pang, S; Corselli, M;Zhang, X; Peault, B; Ting, K; +Soo, C Dental and Craniofacial Research Institute and the Section of Orthodontics, School of Dentistry, UCLA, + 2 UCLA and Orthopaedic Hospital Department of Orthopaedic Surgery, and the Orthopaedic Hospital Research Center, University of California, Los Angeles, Los ...
متن کاملHuman Adipose Derived Stromal Cells Heal Critical Size Mouse Calvarial Defects
BACKGROUND Human adipose-derived stromal cells (hASCs) represent a multipotent cell stromal cell type with proven capacity to differentiate along an osteogenic lineage. This suggests that they may be used to heal defects of the craniofacial or appendicular skeleton. We sought to substantiate the use of undifferentiated hASCs in the regeneration of a non-healing mouse skeletal defect. METHODOL...
متن کاملNegative pressure therapy stimulates healing of critical-size calvarial defects in rabbits
Negative pressure therapy (NPT) is the controlled application of subatmospheric pressure to wounds. It has been shown to stimulate healing across a broad spectrum of soft-tissue wounds, at least in part from the application of mechanical stress on cells and tissues in the wound environment. This study tests the hypothesis that application of NPT to cranial critical-size defects (CSD) in skeleta...
متن کاملSmall Intestine Submucosa Facilitates the Repair of Critical Size Calvarial Defects in Mice
Introduction Selecting an appropriate biomaterial for bone tissue engineering is critical for a successful outcome. Small intestine submucosa (SIS) is an acellular, naturally occurring collagenous extracellular matrix material derived from the submucosa of porcine small intestine, which contains bioactive molecules such as TGF-β and bFGF (1). While SIS has primarily been used for the repair of ...
متن کاملComparative evaluation of nanofibrous scaffolding for bone regeneration in critical-size calvarial defects.
In a previous study we found that nanofibrous poly(l-lactic acid) (PLLA) scaffolds mimicking collagen fibers in size were superior to solid-walled scaffolds in promoting osteoblast differentiation and bone formation in vitro. In this study we used an in vivo model to confirm the biological properties of nanofibrous PLLA scaffolds and to evaluate how effectively they support bone regeneration ag...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2015
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2014.10.010